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Resatorvid

Resatorvid

Item no.	TMO-TQ0181-10mM
Manufacturer	TargetMol
Amount	1mL*10mM(inDMSO)
Category	SALE Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	243984-11-4
Available
purity	100.00%
formula	C15H17ClFNO4S
MolWt	361.82
Pathway	Apoptosis; Immunology/Inflammation
Target	TLR; TNF
Bioactivity	Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).
Reference	Ni JQ, et al. Role of toll-like receptor 4 on lupus lung injury and atherosclerosis in LPS-challenge ApoE-/- mice. Clin Dev Immunol. 2013; 2013:476856.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mL*10mM(inDMSO)

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Delivery expected until 8/2/2024