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hSMG-1 inhibitor 11j

hSMG-1 inhibitor 11j

Item no.	TMO-T8884-10mg
Manufacturer	TargetMol
CASRN	1402452-15-6
Amount	10mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Smiles	O=C(NC1=CC=C(C=C1)C2=NC=CC(=C2)C3=NC(=NC=C3)NC4=CC=C(Cl)C(=C4)S(=O)(=O)N(CC)CC)NC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Short Description	hSMG-1 inhibitor 11j is a pyrimidine derivative. hSMG-1 inhibitor 11j is a potent and selective inhibitor of hSMG-1, IC50 = 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer.
Shipping	cool pack
Storage	-20°
Molecular Weight	566, 07
Pathway	PI3K/Akt/mTOR signaling
Target	PI3K\|\|\|mTOR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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Delivery expected until 8/30/2024

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