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Dot1L-IN-4

Dot1L-IN-4

Item no.	TMO-T8881-5mg
Manufacturer	TargetMol
CASRN	2565705-02-2
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.56%
Citations	Stauffer F, Weiss A, Scheufler C, et al. New Potent DOT1L Inhibitors for in Vivo Evaluation in Mouse. ACS Med Chem Lett. 2019;10(12):1655-1660. Published 2019 Dec 4. doi:10.1021/acsmedchemlett.9b00452
Smiles	ClC1=C([C@H](NC2=C(NC3=NC(OC)=NC(N4CCNCC4)=N3)C=C(S(C)(=O)=O)C=C2)C5=C6OC(F)(OC6=CC=C5)F)N=CC=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2565705-02-2, Histone Methyltransferase, N1-[(3-Chloro-pyridin-2-yl)-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-methyl]-4-methanesulfonyl-N2-(4-methoxy-6-piperazin-1-yl-[1,3,5]triazin-2-yl)-benzene-1,2-diamine
Available
Short Description	CMP 10 (Dot1L-IN-4) is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor.
Shipping	cool pack
Storage	-20°
Target names or alias	N1-[(3-Chloro-pyridin-2-yl)-(2, 2-difluoro-benzo[1, 3]dioxol-4-yl)-methyl]-4-methanesulfonyl-N2-(4-methoxy-6-piperazin-1-yl-[1, 3, 5]triazin-2-yl)-benzene-1, 2-diamine
Molecular Weight	661, 08
Pathway	Chromatin/Epigenetic
Target	Histone Methyltransferase

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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