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Poziotinib hydrochloride

Poziotinib hydrochloride

Item no.	TMO-T8758-5mg
Manufacturer	TargetMol
CASRN	1429757-68-5
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.69%
Citations	Nam HJ, et al. Cancer Lett. 2011, 302(2), 155-165.
Smiles	Cl.COc1cc2ncnc(Nc3ccc(Cl)c(Cl)c3F)c2cc1OC1CCN(CC1)C(=O)C=C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1429757-68-5, HM 781-36B hydrochloride , NOV120101 hydrochloride
Available
Short Description	Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.
Shipping	cool pack
Storage	-20°
Target names or alias	HM 781-36B hydrochloride , NOV120101 hydrochloride
Molecular Weight	527, 8
Pathway	Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling\|\|\|Angiogenesis
Target	EGFR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 8/30/2024

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