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Endomorphin 2

Endomorphin 2

Item no.	TMO-T7218-500mg
Manufacturer	TargetMol
CASRN	141801-26-5
Amount	500mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Formula	C32H37N5O5
Smiles	N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Opioid Receptor
Available
Bioactivity	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP. EM-2-IR fibers originated from primary afferent fibers form symmetric synaptic connections with motoneurons innervating skeletal muscles of the lower limbs in lamina IX of the spinal ventral horn and EM-2 might exert inhibitory effects on the activities of these motoneurons through both presynaptic and postsynaptic mechanisms.
Molwt	571, 678
Pathway	GPCR/G Protein\|\|\|Endocrinology/Hormones\|\|\|Neuroscience

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Amount: 500mg

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