Comparison

Desmethyl Erlotinib hydrochloride European Partner

Item no. TMO-T6619-100mg
Manufacturer TargetMol
CASRN 183320-51-6
Amount 100mg
Category
Type Inhibitor
Specific against other
Purity 0,9903
Formula C21H22ClN3O4
Smiles Cl.COCCOC1=CC2=C(C=C1OCCO)C(NC1=CC=CC(=C1)C#C)=NC=N2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias OSI-420 , OSI420 , CP-473420 , DesMethyl Erlotinib (CP-473420) HCl , Desmethyl Erlotinib , OSI 420
Available
Short Description
Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for human EGFR and EGFR autophosphorylation in tumor cells.
Shipping
cool pack
Storage
-20°
Target names or alias
OSI-420 , OSI420 , CP-473420 , DesMethyl Erlotinib (CP-473420) HCl , Desmethyl Erlotinib , OSI 420
Molecular Weight
415, 87
Pathway
Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Metabolism
Target
Drug Metabolite|||EGFR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100mg
Available: In stock
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