Comparison

CSF1R-IN-3 European Partner

Item no. TMO-T64066-50mg
Manufacturer TargetMol
CASRN 2760584-90-3
Amount 50 mg
Category
Type Inhibitors
Specific against other
Smiles C(=C\1/C=2C(=CC(NC(NC=3C=C(C(C)(C)C)ON3)=O)=CC2)NC1=O)\C4=C(C)C(NC(CN5CCN(C)CC5)=O)=C(C)N4
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Short Description
CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM. CSF1R-IN-3 has anti-proliferative activity against colorectal cancer cells. CSF1R-IN-3 exhibits anti-tumour effects and immune enhancing effects by inhibiting the migration of macrophages and inducing the reprogramming of M2-type macrophages to M1-type macrophages, thus exhibited activity against colorectal cancer cells.
Shipping
cool pack
Storage
-20°
Molecular Weight
574, 67
Pathway
Tyrosine Kinase/Adaptors
Target
CSF-1R|||c-Fms

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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