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NRX-252114

NRX-252114

Item no.	TMO-T63516-50mg
Manufacturer	TargetMol
CASRN	2763260-39-3
Amount	50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	N#CC1=CC=CC2=C1CN(C(=O)C=3C(=O)NC(=CC3SC=4C(Cl)=CC=CC4Cl)C(F)(F)F)C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	NRX252114 , NRX 252114
Available
Short Description	NRX-252114 induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
Shipping	cool pack
Storage	-20°
Target names or alias	NRX252114 , NRX 252114
Molecular Weight	510, 32
Pathway	Cytoskeletal Signaling\|\|\|Stem Cells
Target	Wnt/beta-catenin

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 10/4/2024

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