« Back
Home /
RP-6685

RP-6685

Item no.	TMO-T60187-10mg
Manufacturer	TargetMol
CASRN	2832047-80-8
Amount	10 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	O=C(N(C1=CC=C(F)C=C1)CC#CC2=NN=C(N)C=C2)CC3=NC=C(C=C3C(F)(F)F)C(F)(F)F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Short Description	RP-6685, a highly potent and selective inhibitor of DNA polymerase theta (Polθ), manifests remarkable oral activity. With an IC 50 value of 5.8 nM in the PicoGreen assay, RP-6685 effectively hinders the enzymatic activity of Polθ. In addition, it demonstrates significant antitumor efficacy as observed in a mouse tumor xenograft model [1].
Shipping	cool pack
Storage	-20°
Molecular Weight	497, 37
Pathway	DNA Damage/DNA Repair\|\|\|Cell Cycle/Checkpoint
Target	DNA/RNA Synthesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 10 mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 1 days

Compare

Add to wishlist

Recommend by mail