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Oritinib

Oritinib

Item no.	TMO-T60076-100mg
Manufacturer	TargetMol
CASRN	2035089-28-0
Amount	100mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Smiles	O=C(C=C)NC1=CC(NC=2N=CC=C(N2)C=3C=4C=CC=CC4N5C3CCCC5)=C(OC)C=C1N(C)CCN(C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SH-1028
Available
Short Description	Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
Shipping	cool pack
Storage	-20°
Target names or alias	SH-1028
Molecular Weight	539, 67
Pathway	JAK/STAT signaling\|\|\|Angiogenesis\|\|\|Tyrosine Kinase/Adaptors
Target	EGFR

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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Delivery expected until 8/16/2024

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