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2R,6R-Hydroxynorketamine hydrochloride

2R,6R-Hydroxynorketamine hydrochloride

Item no.	TMO-T41217-5mg
Manufacturer	TargetMol
CASRN	1430202-69-9
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Bioactivity	2R, 6R-Hydroxynorketamine hydrochloride is a ketamine metabolite. Enhances AMPA receptor-mediated excitatory post-synaptic potentials in the CA1 region of hippocampal slices. Decreases intracellularD-serine (a NMDA co-agonist) concentrations in PC-12 cells (IC50 = 0.68 nM). Exerts antidepressant effects in mice. Lacks ketamine-related side effects.

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Amount: 5mg

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