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IL-4-inhibitor-1

IL-4-inhibitor-1

Item no.	TMO-T36527-1mg
Manufacturer	TargetMol
CASRN	1332184-63-0
Amount	1mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Smiles	N#CC1=C(N=C(C=C1C=2C=CC(O)=C(O)C2)C=3C=CC(F)=CC3)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Short Description	IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 μM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 μM). It is selective for IL-4 over IL-13 (EC50= 18.2 μM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 μM), indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway.
Shipping	cool pack
Storage	-20°
Molecular Weight	321, 31
Pathway	Immunology/Inflammation
Target	IL Receptor

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

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Delivery expected until 8/23/2024

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