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Quinacrine analog 34

Quinacrine analog 34

Item no.	TMO-T35747-5mg
Manufacturer	TargetMol
CASRN	1411646-44-0
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Smiles	ClC=1C=CC2=C(N=C3C(=C2NCCN4CCN(C)CC4)CCCC3)C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Short Description	Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels of the autophagy biomarker LC3-II and to induce lysosome deacidification.
Shipping	cool pack
Storage	-20°
Molecular Weight	358, 91

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Amount: 5mg

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Delivery expected until 8/30/2024

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