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TAS-119

TAS-119

Item no.	TMO-T34787-1mg
Manufacturer	TargetMol
CASRN	1453099-83-6
Amount	1 mg
Quantity options	100 mg 10 mg 1 mL 1 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	Cc1cc(Nc2nc(CC3(CCN(CC3)C(=O)c3cccc(Cl)c3Cl)C(O)=O)ccc2F)n[nH]1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TAS-2104, TAS 119, TAS119, TAS 2104, TAS2104
Shipping condition	Cool pack
Available
Manufacturer - Targets	Aurora Kinase
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	506, 36
Target names or alias	TAS2104 , TAS 2104 , TAS-2104 , TAS119 , TAS 119
Description	TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95 nM.TAS-119 has a higher affinity for Aurora A than for Aurora B.TAS-119 exhibits potent antitumor activity and potential antimitotic activity. TAS-119 has potent anti-tumor activity and potential anti-mitotic activity.
Pathways	Chromatin/Epigenetic\|\|\|Cell Cycle/Checkpoint

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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