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Imarikiren HCl

Imarikiren HCl

Manufacturer	TargetMol
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Amount	5mg
Item no.	TMO-T27595-5mg
CASRN	1202269-24-6
eClass 6.1	30220300
eClass 9.0	32160605
Available
Alias	TAK-272 HCl. Imarikiren HCl \| , TAK-272 , TAK-272 hydrochloride , TAK272 , TAK 272
Purity	0,98
Short Description	Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic proteases, such as cathepsin D (IC50 > 10 μM) and pepsin (IC50 > 10 μM). TAK-272 exhibits a dramatically improved PK profile in rats (F = 25.2%). TAK-272 (3 and 10 mg/kg, p.o.) exhibits potent and long-lasting antihypertensive efficacy in a dose-dependent manner.
Shipping	cool pack
Storage	-20°
Target names or alias	TAK-272 HCl. Imarikiren HCl \| , TAK-272 , TAK-272 hydrochloride , TAK272 , TAK 272
Molecular Weight	536, 11

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 7/26/2024

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