Comparison

Laduviglusib trihydrochloride European Partner

Item no. TMO-T22657-1mL
Manufacturer TargetMol
CASRN 1782235-14-6
Amount 1 mL
Category
Type Inhibitors
Specific against other
Smiles Cl.Cl.Cl.Cc1cnc([nH]1)-c1c[nH]\c(=N/CC\N=c2\ccc(c[nH]2)C#N)nc1-c1ccc(Cl)cc1Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias CHIR 99021 trihydrochloride , CT99021 trihydrochloride
Available
Short Description
Laduviglusib trihydrochloride is a selective glycogen synthase kinase 3 (GSK-3) inhibitor with IC50s of 10 nM and 6.7 nM for GSK-3α and GSK-3β. Laduviglusib trihydrochloride inhibits human GSK-3β with a Ki of 9.8 nM. Laduviglusib trihydrochloride is an activator of Wnt/β-catenin signaling. Laduviglusib trihydrochloride induces autophagy.
Shipping
cool pack
Storage
-20°
Target names or alias
CHIR 99021 trihydrochloride , CT99021 trihydrochloride
Molecular Weight
574, 72
Pathway
Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Stem Cells
Target
Wnt/beta-catenin|||GSK-3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL
Available: In stock
available

Delivery expected until 8/23/2024 

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