NVP-2

Item no.	TMO-T16363-500mg
Manufacturer	TargetMol
CASRN	1263373-43-8
Amount	500mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,9976
Formula	C27H37ClN6O2
Smiles	COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Apoptosis, CDK
Available
Bioactivity	NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 μM, 0.706 μM, and 0.605 μM, respectively).
Molwt	513, 08
Pathway	Cell Cycle/Checkpoint\|\|\|Apoptosis

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Amount: 500mg

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