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JBJ-04-125-02

JBJ-04-125-02

Item no.	TMO-T11714-5mg
Manufacturer	TargetMol
CASRN	2060610-53-7
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	0,98
Smiles	[C@@H](C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C4=CC=C(C=C4)N5CCNCC5)C6=C(O)C=CC(F)=C6
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	JAK
Available
Short Description	JBJ-04-125-02 can inhibit cancer cell proliferation and EGFRL858R/T790M/C797S signaling. JBJ-04-125-02 has anti-tumor activities. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor with an IC50 of 0.26 nM for EGFRL858R/T790M.
Shipping	cool pack
Storage	-20°
Molecular Weight	543, 61
Pathway	JAK/STAT signaling\|\|\|Chromatin/Epigenetic\|\|\|Stem Cells\|\|\|Angiogenesis
Target	JAK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 9/6/2024

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