Comparison

CCR4 antagonist 2 European Partner

Item no. TMO-T10713-50mg
Manufacturer TargetMol
CASRN 2206788-99-8
Amount 50 mg
Category
Type Inhibitors
Specific against other
Smiles [C@H](C)(N1C=2C(C(C#N)=N1)=NC=C(N2)C=3C[C@@H](C)[C@](CC3)(N4[C@H](CO)CCC4)[H])C5=C(Cl)C=C(Cl)C=C5
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Short Description
CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively.
Shipping
cool pack
Storage
-20°
Molecular Weight
511, 45
Pathway
Metabolism|||Membrane transporter/Ion channel
Target
Calcium Channel

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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