AM9405

Item no.	TMO-T10294-5mg
Manufacturer	TargetMol
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	OC1=C(C2=[N+](C)C(C=CC=C3)=C3N2C)C(O)=CC(C(C)(C)CCCCCC)=C1.[Br-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Short Description	AM9405 is a novel peripherally active cannabinoid type 1 (CB1) and serotonin type 3 receptor agonist. AM9405 inhibits twitch contraction of the ileum and the colon with IC 50 s of 45.71 and 0.076 nM, respectively. AM9405 significantly slowed mouse intestinal motility in physiological conditions. Moreover, AM9405 reversed hypermotility and reduced pain in mouse models mimicking symptoms of functional GI disorders, such as stress-induced diarrhea and writhing test.
Shipping	cool pack
Storage	-20°
Molecular Weight	461, 44
Pathway	GPCR/G Protein\|\|\|Neuroscience
Target	5-HT Receptor

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Amount: 5 mg

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Delivery expected until 8/23/2024

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