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LY2886721

LY2886721

Item no.	S2156-1000
Manufacturer	Selleckchem
CASRN	1262036-50-9
Amount	1 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BACE, gamma-secretase;Others
Similar products	LY2886721
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Chemical Name	N-(3-((4aS, 7aS)-2-amino-4a, 5, 7, 7a-tetrahydro-4H-furo[3, 4-d][1, 3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide
Clinical Trials	LY2886721 is currently in a Phase II clinical trial in patients with Mild Cognitive Impairment.
Description	LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
In vitro	LY2886721 is an oral, small molecule of beta-site amyloid protein cleaving enzyme (BACE) inhibitor with the potential to inhibit the synthesis of beta-amyloid and thereby to slow the clinical progression of AD. [1] LY2886721 can also targetgamma-secretase to nhibit the synthesis of beta-amyloid. [2]
Molecular Weight (MW)	390, 41
Picture ChemicalStructure Description	LY2886721 Chemical Structure
Solubility (25C)	DMSO 9 mg/mL, Water <1 mg/mL, Ethanol <1 mg/mL
Storage	2 years -20CPowder, 2 weeks4Cin DMSO, 2 months-80Cin DMSO

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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