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Acivicin (hydrochloride)

Acivicin (hydrochloride)

Item no.	HY-W016586A-100mg
Manufacturer	MedChem Express
CASRN	161922-40-3
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.14
Formula	C5H8Cl2N2O3
Citations	[1]Delphine Waniusiow, et al. Toluene-induced hearing loss in acivicin-treated rats. Neurotoxicol Teratol. May-Jun 2008;30(3):154-60.<br/>[2]Kreuzer J, et al. Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition. Chem Sci. 2014 Dec 1;6(1):237-245. Epub 2014 Sep 26.<br/>[3]Chikhale EG, et al. Carrier-mediated transport of the antitumor agent acivicin across the blood-brain barrier. Biochem Pharmacol. 1995 Mar 30;49(7):941-5.
Smiles	[H]Cl.ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AT-125 (hydrochloride); U-42126 (hydrochloride)
Similar products	161922-40-3
Available
Product Description	Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	215.03
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Infection
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Parasite
Manufacturers Target	Parasite
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Natural Products

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