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Oxaloacetic acid

Oxaloacetic acid

Item no.	HY-W010382-10mM
Manufacturer	MedChem Express
CASRN	328-42-7
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.88
Formula	C4H4O5
Citations	[1]F. L. Breusch. The fate of oxaloacetic acid in different organs. Biochem J. 1939 Nov; 33(11): 1757-1770.<br>[2]Brian D Fink, et al. Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem. 2018 Dec 21;293(51):19932-19941.<br>[3]Li W, et al. Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction. Front Pharmacol. 2022 Oct 13;13:1029775.
Smiles	O=C(O)C(CC(O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2-Oxosuccinic acid
Available
Product Description	Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function[1][2][3].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	132.07
Clinical_Information	Phase 1
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : ≥ 100 mg/mL\|H2O : ≥ 100 mg/mL
Manufacturers Target	Endogenous Metabolite; Reactive Oxygen Species
Isoform	Human Endogenous Metabolite
Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

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HY-W010382-10mM-safety-datasheet.pdf