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1-(4-Chlorobenzhydryl)piperazine

1-(4-Chlorobenzhydryl)piperazine

Item no.	HY-W001978-1ea
Manufacturer	MedChem Express
CASRN	303-26-4
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Formula	C17H19ClN2
Citations	[1]Gaertner, HJ, Breyer, U., and Liomin, G.Chronic administration of chlorcyclizine and meclizine to rats: Accumulation of a metabolite formed by piperazine ring cleavage J. Pharmacol. Exp. Ther.185(2)195-201(1973)<br>[2]Kuntzman, R., Klutch, A., Tsai, I., et al.Physiological distribution and metabolic inactivation of chlorcyclizine and cyclizineJ. Pharmacol. Exp. Ther.149(1)29-35(1965)<br>[3]Simpson, D., Skellern, GG, and Miller, JHMethod for the control of known impurities in hydroxyzine hydrochlorideJ. Pharm . Biomed. Anal.14(8-10)1371-1375(1996)<br>[4]Javid, FS, Shafaat, A., and Zarghi, A. Determination of cetirizine and its impurities in bulk and tablet formulation using a validated capillary zone electrophoretic methodJ. Anal. Chem.69(5)442-447(2014)<br>[5]Back, SK, Kam, YL, Oh, JA, et al.Synthesis and evaluation of (4-chlorobenzhydryl) piperazine amides as sodium channel Nav7 inhibitorsBull. Korean Chem. Soc.36(9)2290-2297(2015)<br>[6]Yarim, M., Koksal, M., Durmaz, I., et al.Cancer cell cytotoxicities of 1-(4-substitutedbenzoyl)-4 -(4-chlorobenzhydryl)piperazine derivativesInt. J. Mol. Sci.13(7)8071-8085(2012)<br>[7]Narsaiah, AV, and Narssimha, P.Efficient synthesis of antihistamines clocinizine and chlorcyclizineMed. Chem. Res.21538- 541 (2012)
Smiles	ClC1=CC=C(C(N2CCNCC2)C3=CC=CC=C3)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	286.80
Clinical_Information	No Development Reported
Manufacturers Research_Area	Others
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturers Target	Biochemical Assay Reagents
Pathway	Others
Manufacturers Product type	Biochemical Assay Reagents

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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