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Ianalumab

Ianalumab

Item no.	HY-P99653-1ea
Manufacturer	MedChem Express
CASRN	1929549-92-7
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	95.00
Dry ice	Yes
Citations	[1]McWilliams EM, et al. Anti-BAFF-R antibody VAY-736 demonstrates promising preclinical activity in CLL and enhances effectiveness of ibrutinib. Blood Adv. 2019 Feb 12;3(3):447-460.
Smiles	[Ianalumab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	VAY-736
Available
Product Description	Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM)[1].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	N/A
Clinical_Information	Phase 3
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Others
Pathway	Others
Manufacturers Product type	Inhibitory Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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