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Tengonermin

Tengonermin

Item no.	HY-P99565-5mg
Manufacturer	MedChem Express
CASRN	1960461-99-7
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Citations	[1]Valentinis B, et, al. Mechanism of Action of the Tumor Vessel Targeting Agent NGR-hTNF: Role of Both NGR Peptide and hTNF in Cell Binding and Signaling. Int J Mol Sci. 2019 Sep 12;20(18):4511. <br>[2]Gregorc V, et, al. NGR-hTNF in combination with best investigator choice in previously treated malignant pleural mesothelioma (NGR015): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Oncol. 2018 Jun;19(6):799-811.
Smiles	[Tengonermin]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ARENEGYR; NGR-TNF; NGR-hTNF
Available
Product Description	Tengonermin (ARENEGYR) is a vascular-targeting agent consisting of the human Tumour Necrosis Factor-α (TNF-α) conjugated with the CNGRCG peptide. Tengonermin increases penetration of intratumoral chemotherapy and T-cell infiltration by modifying the tumour microenvironment[1][2].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	N/A
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	H2O
Pathway	Apoptosis
Manufacturers Product type	Inhibitory Antibodies

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