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Loncastuximab tesirine

Loncastuximab tesirine

Item no.	HY-P99349-200ug
Manufacturer	MedChem Express
CASRN	1879918-31-6
Amount	200 ug
Quantity options	100 ug 1 ea 1 mg 200 ug 500 ug 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.37
Dry ice	Yes
Citations	[1]Nikoleta Sachini, et al. Combination of Loncastuximab Tesirine and Polatuzumab Vedotin Shows Increased Anti-Tumor Activity in Pre-Clinical Models of Non-Hodgkin Lymphoma. Blood. 2021.<br/>[2]Zammarchi F, et al. ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies. Blood. 2018 Mar 8;131(10):1094-1105.
Smiles	[Loncastuximab tesirine]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Loncastuximab tesirine-lpyl; ADCT-402
Available
Product Description	Loncastuximab tesirine is a human cluster of differentiation 19 (CD19)-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis, it can be used for the research of diffuse large B-cell lymphoma[1][2].
StorageTemperature	-80°C, protect from light
Shipping	Dry Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	147000 (average)
Clinical Information	Launched
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	Antibody-Drug Conjugates (ADCs); Apoptosis
Manufacturers Target	Antibody-Drug Conjugates (ADCs); Apoptosis
Manufacturers Pathway	Antibody-drug Conjugate/ADC Related; Apoptosis
Manufacturers Product type	ADC Related

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Amount: 200 ug

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