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Tesidolumab

Tesidolumab

Item no.	HY-P99322-1mg
Manufacturer	MedChem Express
CASRN	1531594-08-7
Amount	1 mg
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	97.01
Dry ice	Yes
Citations	[1]Jun-Ichi Nishimura, et al. Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria. Haematologica. 2022 Jun 1;107(6):1483-1488.
Smiles	[Tesidolumab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	LFG316; Anti-Human C5 Recombinant Antibody
Available
Product Description	Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex[1].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	COVID-19-immunoregulation
Clinical Information	Phase 2
Manufacturers Research Area	Inflammation/Immunology
Solubility	10 mM in H2O
Target	Complement System
Manufacturers Target	Complement System
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Inhibitory Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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