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Teneliximab

Teneliximab

Item no.	HY-P99321-1mg
Manufacturer	MedChem Express
CASRN	299423-37-3
Amount	1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.0
Dry ice	Yes
Citations	[1]Maria A Argiriadi, et al. CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol. 2019 Aug 5;20(1):29.<br>[2]Andrew B Adams, et al. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol. 2005 Jan 1;174(1):542-50.
Smiles	[Teneliximab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BMS 224819; Chi220; Anti-Human CD40 Recombinant Antibody
Available
Product Description	Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	N/A
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Inflammation/Immunology
Solubility	10 mM in H2O
Pathway	Apoptosis
Manufacturers Product type	Inhibitory Antibodies

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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