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Guselkumab

Guselkumab

Item no.	HY-P9931-5mg
Manufacturer	MedChem Express
CASRN	1350289-85-8
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.97
Dry ice	Yes
Citations	[1]International non-proprietary name: guselkumab Procedure No. EMEA/H/C/004271/0000par-public-assessment-report_en.pdf<br>[2]Li Li, et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int Immunopharmacol
Smiles	[Guselkumab]
ECLASS 5.1	32169090
ECLASS 6.1	32169090
ECLASS 8.0	32169090
ECLASS 9.0	32169090
ECLASS 10.0.1	32169090
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CNTO 1959
Available
Product Description	Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	N/A
Clinical_Information	Launched
Manufacturers Research_Area	Inflammation/Immunology
Solubility	H2O
Manufacturers Target	Interleukin Related
Isoform	IL-23
Pathway	Immunology/Inflammation
Manufacturers Product type	Inhibitory Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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