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Guselkumab

Guselkumab

Item no.	HY-P9931-1mg
Manufacturer	MedChem Express
CASRN	1350289-85-8
Amount	1 mg
Quantity options	1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.97
Dry ice	Yes
Citations	[1]International non-proprietary name: guselkumab Procedure No. EMEA/H/C/004271/0000par-public-assessment-report_en.pdf [2]Li Li, et al. IBI112, a selective anti-IL23p19 monoclonal antibody, displays high efficacy in IL-23-induced psoriasiform dermatitis. Int Immunopharmacol
Smiles	[Guselkumab]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CNTO 1959
Shipping condition	Dry ice
Available
Product Description	Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research[1].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	COVID-19-immunoregulation
Clinical Information	Launched
Manufacturers Research Area	Inflammation/Immunology
Solubility	H2O
Target	Interleukin Related
Manufacturers Target	Interleukin Related
Isoform	IL-23
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Inhibitory Antibodies

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P9931-1mg-safety-datasheet.pdf