« Back
Home /
Ulocuplumab

Ulocuplumab

Item no.	HY-P99272-5mg
Manufacturer	MedChem Express
CASRN	1375830-34-4
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.90
Dry ice	Yes
Citations	[1]Kashyap MK, et al. Ulocuplumab (BMS-936564 / MDX1338): a fully human anti-CXCR4 antibody induces cell death in chronic lymphocytic leukemia mediated through a reactive oxygen species-dependent pathway. Oncotarget. 2016 Jan 19;7(3):2809-22. <br>[2]Kuhne MR, et al. BMS-936564/MDX-1338: a fully human anti-CXCR4 antibody induces apoptosis in vitro and shows antitumor activity in vivo in hematologic malignancies. Clin Cancer Res. 2013 Jan 15;19(2):357-66.
Smiles	[Ulocuplumab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody
Available
Product Description	Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti-CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL). Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models[1][2].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	146.2 (kDa)
Clinical_Information	Phase 2
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	CXCR
Isoform	CXCR4
Pathway	GPCR/G Protein; Immunology/Inflammation
Manufacturers Product type	Inhibitory Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

available

Request delivery time