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Lenzilumab

Lenzilumab

Item no.	HY-P99207-1mg
Manufacturer	MedChem Express
CASRN	1229575-09-0
Amount	1 mg
Quantity options	10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.64
Dry ice	Yes
Citations	[1]Rosalie M Sterner, et al. GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood. 2019 Feb 14;133(7):697-709.<br/>[2]Zelalem Temesgen, et al. GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia: A Case-Cohort Study. Mayo Clin Proc. 2020 Nov;95(11):2382-2394.
Smiles	[Lenzilumab]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	KB 003
Available
Product Description	Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies[1][2].
StorageTemperature	Store at -80°C for 2 years
Shipping	Dry Ice
Manufacturers Applications	Cancer-programmed cell death
Clinical Information	Phase 3
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	SARS-CoV
Manufacturers Target	SARS-CoV
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Inhibitory Antibodies

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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