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ACVR2B, Mouse (HEK293, His)

ACVR2B, Mouse (HEK293, His)

Item no.	HY-P75536-100ug
Manufacturer	MedChem Express
Amount	100 ug
Quantity options	100 ug 10 ug 2 ug 50 ug
Category	Inhibitors & Compound Libraries Compound Libraries
Type	Peptides
Specific against	other
Purity	90.00
Sequence	SGRGEAETR ECIYYNANWE LERTNQSGLE RCEGEQDKRL HCYASWRNSS GTIELVKKGC WLDDFNCYDR QECVATEENP QVYFCCCEGN FCNERFTHLP EPGGPEVTYE PPPTAPT
Citations	[1]Johanna Magga, et al. Systemic Blockade of ACVR2B Ligands Protects Myocardium from Acute Ischemia-Reperfusion Injury. Mol Ther. 2019 Mar 6;27(3):600-610. [2]Oddrun Elise Olsen, et al. Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B. Cell Commun Signal. 2015 Jun 6;13:27. [3]Rafael Barreto, et al. ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass. Sci Rep. 2017 Oct 31;7(1):14470.
Smiles	SGRGEAETR ECIYYNANWE LERTNQSGLE RCEGEQDKRL HCYASWRNSS GTIELVKKGC WLDDFNCYDR QECVATEENP QVYFCCCEGN FCNERFTHLP EPGGPEVTYE PPPTAPT
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ACVR2B Protein, Mouse (HEK293, His),Mouse,HEK293
Available
Product Description	ACVR2B is a type II member of the TGF-β family of receptor Serine/Threonine kinases. ACVR2B binds to activins and growth differentiation factors (GDF), which in turn activate type I receptors, activating downstream molecule SMAD2/3[1]. ACVR2B Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 134 amino acids (M1-T134).
StorageTemperature	Stored at -20°C for 2 years
Shipping	Blue Ice
MolecularWeight	23-37 kDa
Manufacturers Product type	Recombinant Proteins

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Amount: 100 ug

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