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Nicastrin, Human (HEK293, His)

Nicastrin, Human (HEK293, His)

Item no.	HY-P74698-20ug
Manufacturer	MedChem Express
Amount	20 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Peptides
Specific against	other
Purity	98.0
Smiles	NSVERKIYIP LNKTAPCVRL LNATHQIGCQ SSISGDTGVI HVVEKEEDLQ WVLTDGPNPP YMVLLESKHF TRDLMEKLKG RTSRIAGLAV SLTKPSPASG FSPSVQCPND GFGVYSNSYG PEFAHCREIQ WNSLGNGLAY EDFSFPIFLL EDENETKVIK QCYQDHNLSQ NGSAPTFPLC AMQLFSHMHA VISTATCMRR SSIQSTFSIN PEIVCDPLSD YNVWSMLKPI NTTGTLKPDD RVVVAATRLD SRSFFWNVAP GAESAVASFV TQLAAAEALQ KAPDVTTLPR NVMFVFFQGE TFDYIGSSRM VYDMEKGKFP VQLENVDSFV ELGQVALRTS LELWMHTDPV SQKNESVRNQ VEDLLATLEK SGAGVPAVIL RRPNQSQPLP PSSLQRFLRA RNISGVVLAD HSGAFHNKYY QSIYDTAENI NVSYPEWLSP EEDLNFVTDT AKALADVATV LGRALYELAG GTNFSDTVQA DPQTVTRLLY GFLIKANNSW FQSILRQDLR SYLGDGPLQH YIAVSSPTNT TYVVQYALAN LTGTVVNLTR EQCQDPSKVP SENKDLYEYS WVQGPLHSNE TDRLPRCVRS TARLARALSP AFELSQWSST EYSTWTESRW KDIRARIFLI ASKELE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Nicastrin Protein, Human (HEK293, His),Human,HEK293
Available
Product Description	Nicastrin Protein, a crucial gamma-secretase complex subunit, catalyzes intramembrane cleavage of Notch receptors and APP. Operating in Notch and Wnt signaling, the complex modulates regulatory proteins and CTNNB1 levels. Collaborating with PSEN1/2, APH1A/B, and PSENEN/PEN2, Nicastrin binds to proteolytically processed C83 and C99 fragments, emphasizing its pivotal role in molecular pathways and cellular processes. Nicastrin Protein, Human (HEK293, His) is the recombinant human-derived Nicastrin protein, expressed by HEK293 , with C-His labeled tag. The total length of Nicastrin Protein, Human (HEK293, His) is 636 a.a., with molecular weight of 110-120 kDa.
StorageTemperature	Stored at -20°C for 2 years
Shipping	Blue Ice
MolecularWeight	Approximately 105-125 kDa
Manufacturers Product type	Recombinant Proteins

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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