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Chemerin-9 (149-157)

Chemerin-9 (149-157)

Item no.	HY-P1844-1ea
Manufacturer	MedChem Express
CASRN	676367-27-4
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Formula	C54H66N10O13
Citations	Hypertension. 2024 Feb 15.<br>Eur J Pharmacol. 2022 Oct 25;175343.<br>[1]Tu J, et, al. Regulatory effect of chemerin and therapeutic efficacy of chemerin 9 in pancreatogenic diabetes mellitus. Mol Med Rep. 2020 Mar;21(3):981-988.<br>[2]Chen S, et, al. Chemerin-9 Attenuates Experimental Abdominal Aortic Aneurysm Formation in ApoE-/- Mice. J Oncol. 2021 Apr 17;2021:6629204.<br>[3]Lei Z, et, al. Chemerin-9 Peptide Enhances Memory and Ameliorates Aβ1-42-Induced Object Memory Impairment in Mice. Biol Pharm Bull. 2020 Feb 1;43(2):272-283.<br>[4]Yamamoto A, et, al. Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro. Eur J Pharmacol. 2021 Dec 5;912:174566.
Smiles	OC[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(N)=O)NC(CNC([C@H]3N(C([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CC=C(O)C=C5)N)=O)=O)CCC3)=O)=O)=O)=O)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Chemerin-9 (149-157) is a potent agonist of chemokine-like receptor 1 (CMKLR1) . Chemerin-9 (149-157) has anti-inflammatory activity. Chemerin-9 (149-157) stimulates phosphorylation of Akt and ERK as well as ROS production. Chemerin-9 (149-157) ameliorates Aβ1-42-induced memory impairmen. Chemerin-9 (149-157) regulates immune responses, adipocyte differentiation, and glucose metabolism[1][2][3][4].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	1063.16
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	H2O
Manufacturers Target	Akt; Amyloid-β; Chemerin Receptor; ERK; Reactive Oxygen Species
Pathway	GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; PI3K/Akt/mTOR; Stem Cell/Wnt
Manufacturers Product type	Peptides

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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