Comparison

TLQP-21 (TFA) European Partner

Item no. HY-P1345A-1mg
Manufacturer MedChem Express
Amount 1 mg
Quantity options 10 mg 1 mg 5 mg
Category
Type Peptides
Specific against other
Purity 99.90
Formula C109H171F3N40O28
Citations [1]Elena Bresciani , et al. TLQP-21, A VGF-Derived Peptide Endowed of Endocrine and Extraendocrine Properties: Focus on In Vitro Calcium Signaling. Int J Mol Sci. 2019 Dec 24;21(1):130.<br/>[2]Cheryl Cero, et al. The TLQP-21 Peptide Activates the G-protein-coupled Receptor C3aR1 via a Folding-Upon-Binding Mechanism. ructure. 2014 Dec 2;22(12):1744-1753.
Smiles O=C(N1[C@@H](CCC1)C(N[C@@H](C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)[C@H]2N(CCC2)C([C@H](CC(C)C)NC([C@H](C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CO)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H]4N(CCC4)C([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC5=CN=CN5)=O)CC6=CC=CC=C6)=O)CC7=CN=CN7)=O)CC8=CN=CN8)=O)=O)=O.O=C(O)C(F)(F)F
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Product Description
TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions[1][2].
StorageTemperature
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping
Blue Ice
Manufacturers Applications
Metabolism-protein/nucleotide metabolism
MolecularWeight
2546.77
Clinical Information
No Development Reported
Manufacturers Research Area
Endocrinology; Neurological Disease
Solubility
H2O : 50 mg/mL (ultrasonic)
Target
Complement System
Manufacturers Target
Complement System
Manufacturers Pathway
Immunology/Inflammation
Manufacturers Product type
Peptides

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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