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GDP-D-mannose (disodium)

GDP-D-mannose (disodium)

Item no.	HY-N7389A-5mg
Manufacturer	MedChem Express
CASRN	103301-73-1
Amount	5 mg
Quantity options	10 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.92
Formula	C16H23N5Na2O16P2
Citations	[1]Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7.
Smiles	O=P(OP(OC1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)(O[Na])=O)(O[Na])OC[C@@H](O2)[C@@H](O)[C@@H](O)[C@@H]2N3C(N=C(N)NC4=O)=C4N=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	649.30
Clinical Information	No Development Reported
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : 11.76 mg/mL (ultrasonic; adjust pH to 3 with 1M HCl)\|H2O : 125 mg/mL (ultrasonic)
Target	Endogenous Metabolite
Manufacturers Target	Endogenous Metabolite
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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