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Aphadilactone C

Aphadilactone C

Item no.	HY-N7281-1ea
Manufacturer	MedChem Express
CASRN	1522004-70-1
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C40H52O8
Citations	[1]Jia Liu, et al. Aphadilactones A-D, four diterpenoid dimers with DGAT inhibitory and antimalarial activities from a Meliaceae plant. J Org Chem. 2014 Jan 17;79(2):599-607.
Smiles	CC(C[C@H]1/C=C(C)/CCC[C@@]2(C(OC(C)3C)=CC3=O)C4=C(OC(C)(C4=O)C)[C@H](CC2)CCC/C(C)=C/[C@@H]5CC(C)=CC(O5)=O)=CC(O1)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Aphadilactone C is a potent and selective DGAT-1 inhibitor with an IC50 of 0.46 μM. Aphadilactone C shows significant antimalarial activities with an IC50 value of 170 nM[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	660.84
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	10 mM in DMSO
Target	Acyltransferase; Parasite
Manufacturers Target	Acyltransferase; Parasite
Manufacturers Pathway	Anti-infection; Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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