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Gamma-Linolenic acid

Gamma-Linolenic acid

Item no.	HY-N7140-5mg
Manufacturer	MedChem Express
CASRN	506-26-3
Amount	5 mg
Quantity options	10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.74
Formula	C18H30O2
Citations	[1]Sergeant S, et al. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15;785:77-86. [2]Youn K, et al. Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways[J]. Journal of Functional Foods, 2018, 42: 30-37. [3]Andreoli Miyake J, et al. Gamma-Linolenic acid alters migration, proliferation and apoptosis in human and rat glioblastoma cells. Prostaglandins Other Lipid Mediat. 2020 Oct;150:106452. [4]Rahimi K, et al. The protective effects of Gamma-linolenic acid against indomethacin-induced gastric ulcer in rats[J]. British Journal of Nutrition, 2024, 131(11): 1844-1851. [5]Khan SA, et al. Gamma-linolenic acid ameliorated glycation-induced memory impairment in rats. Pharm Biol. 2017 Dec;55(1):1817-1823.
Smiles	CCCCC/C=C\C/C=C\C/C=C\CCCCC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	γ-Linolenic acid
Shipping condition	Cool pack
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	Apoptosis; Endogenous Metabolite; ERK; JNK; NF-κB
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	278.43
Product Description	Gamma-linolenic acid (γ-Linolenic acid) is an orally active unsaturated fatty acid. Gamma-linolenic acid exerts anti-inflammatory effects by inhibiting the NF-κB pathway and the phosphorylation of ERK1/2 and JNK. At the same time, it exerts anticancer effects by inducing apoptosis (Apoptosis) in cancer cells. Additionally, Gamma-linolenic acid also has antioxidant and memory-improving effects. It holds promise for research in the fields of inflammation, neurology, and cancer diseases[1][2][3][4][5].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Isoform	ERK1; ERK2; Human Endogenous Metabolite
Clinical information	Launched

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HY-N7140-5mg-safety-datasheet.pdf