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Ethyl Caffeate

Ethyl Caffeate

Item no.	HY-N6966-10mg
Manufacturer	MedChem Express
CASRN	102-37-4
Amount	10 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.91
Formula	C11H12O4
Citations	[1]Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.
Smiles	O=C(OCC)/C=C/C1=CC=C(O)C(O)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	102-37-4
Available
Product Description	Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	208.21
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO : 250 mg/mL (ultrasonic)
Target	COX; NF-κB; NO Synthase; PGE synthase
Manufacturers Target	COX; NF-κB; NO Synthase; PGE synthase
Isoform	COX-2; iNOS; NF-κB
Manufacturers Pathway	Immunology/Inflammation; NF-κB
Manufacturers Product type	Natural Products

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HY-N6966-10mg-safety-datasheet.pdf