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T-2 Toxin

T-2 Toxin

Item no.	HY-N6792-5mg
Manufacturer	MedChem Express
CASRN	21259-20-1
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Food Safety Mycotoxins Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.23
Formula	C24H34O9
Citations	[1]Li Y, et al. T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J Agric Food Chem. 2011 Apr 27;59(8):3441-53.<br>[2].Sun YX, et al. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38(1):80-5
Smiles	C[C@@]12[C@@]3(OC3)[C@@](O[C@@]4([H])[C@@]2(C[C@H](OC(CC(C)C)=O)C(C)=C4)COC(C)=O)([H])[C@H](O)[C@H]1OC(C)=O
ECLASS 5.1	30220300
ECLASS 6.1	30220300
ECLASS 8.0	32160605
ECLASS 9.0	32160605
ECLASS 10.0.1	32160490
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	T-2 Mycotoxin
Similar products	21259-20-1
Available
Product Description	T-2 Toxin (T-2 Mycotoxin) is a toxic trichothecene mycotoxin produced by various Fusarium species in feedstuffs and cereal grains, LD50 values of T-2 Toxin in mice and rats are 5.2 and 1.5 mg/kg BWa, respectively [1]. T-2 Toxin (T-2 Mycotoxin) can be transformed into a variety of metabolite, the typical metabolites of T-2 toxin in animals are HT-2 toxin and T-2-triol, which are hydrolysates[1]. T-2 Toxin (T-2 Mycotoxin) is an inhibitor of protein synthesis resulting from binding peptidyltransferase, which is an integral part of the 60s ribosomal subunit. T-2 Toxin (T-2 Mycotoxin) inhibits the synthesis of DNA and RNA, interferes with the metabolism of membrane phospholipids, and increases the level of liver lipid peroxides[1]. T-2 Toxin (T-2 Mycotoxin) induces apoptosis in the immune system, gastrointestinal tissues, and fetal tissues[2].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	466.52
Clinical_Information	No Development Reported
Manufacturers Research Area	Metabolic Disease
Solubility	DMSO : ≥ 100 mg/mL
Manufacturers Target	Apoptosis; DNA/RNA Synthesis
Pathway	Apoptosis; Cell Cycle/DNA Damage

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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