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Skullcapflavone II

Skullcapflavone II

Item no.	HY-N6624-1mg
Manufacturer	MedChem Express
CASRN	55084-08-7
Amount	1 mg
Quantity options	1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.54
Formula	C19H18O8
Citations	[1]Solnier J, et al. Flavonoids as Novel Efflux Pump Inhibitors and Antimicrobials Against Both Environmental and Pathogenic Intracellular Mycobacterial Species. Molecules. 2020;25(3):734. Published 2020 Feb 7.<br/>[2]Lee J, et al. Skullcapflavone II inhibits osteoclastogenesis by regulating reactive oxygen species and attenuates the survival and resorption function of osteoclasts by modulating integrin signaling. FASEB J. 2019;33(2):2026-2036.<br/>[3]Jang HY, et al. Skullcapflavone II inhibits ovalbumin-induced airway inflammation in a mouse model of asthma [published correction appears in Int Immunopharmacol. 2013 Sep;17(1):154]. Int Immunopharmacol. 2012;12(4):666-674.
Smiles	COC1=C2C(C(C=C(C3=C(C=CC=C3O)OC)O2)=O)=C(O)C(OC)=C1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	55084-08-7
Similar products	55084-08-7
Available
Product Description	Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	374.34
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : 50 mg/mL (ultrasonic)
Target	Bacterial
Manufacturers Target	Bacterial
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Natural Products

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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