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Phosphorylethanolamine

Phosphorylethanolamine

Item no.	HY-N5034-5g
Manufacturer	MedChem Express
CASRN	1071-23-4
Amount	5 g
Quantity options	100 mg 10 mM/1 mL 1 g 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Formula	C2H8NO4P
Citations	[1]Kinoshita Y, et al. Phosphorylethanolamine content of human brain tumors. Neurol Med Chir (Tokyo). 1994 Dec;34(12):803-6. [2]Hui SCN, et al. In vivo spectral editing of phosphorylethanolamine. Magn Reson Med. 2022 Jan;87(1):50-56. [3]Calzada E,et al. Phosphatidylethanolamine Metabolism in Health and Disease. Int Rev Cell Mol Biol. 2016;321:29-88. doi: 10.1016/bs.ircmb.2015.10.001. [4]van der Veen JN, et al. A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling. FASEB J. 2019 Apr;33(4):5045-5057. [5]Nesic I, et al. Alterations in phosphatidylethanolamine levels affect the generation of Aβ. Aging Cell. 2012 Feb;11(1):63-72.
Smiles	NCCOP(O)(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Monoaminoethyl phosphate, NSC 254167, O-Phosphoethanolamine
Shipping condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	141.06
Product Description	Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases[1][2][3][4][5].
Manufacturer - Research Area	Cancer; Metabolic Disease; Neurological Disease
Solubility	H2O : 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Isoform	Human Endogenous Metabolite; Microbial Metabolite
Clinical information	No Development Reported

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HY-N5034-5g-safety-datasheet.pdf