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Britannilactone diacetate

Britannilactone diacetate

Item no.	HY-N4190-1ea
Manufacturer	MedChem Express
CASRN	1286694-67-4
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C19H26O6
Citations	[1]Tang JJ, et al. 1,10-Seco-Eudesmane sesquiterpenoids as a new type of anti-neuroinflammatory agents by suppressing TLR4/NF-κB/MAPK pathways. Eur J Med Chem. 2021 Nov 15;224:113713.
Smiles	O=C1O[C@@]2([H])[C@@]([C@H](OC(C)=O)C([C@@H](C)CCCOC(C)=O)=C(C)C2)([H])C1=C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1,6-O,O-Diacetylbritannilactone; Di-O-acetylbritannilactone
Available
Product Description	Britannilactone diacetate (1, 6-O, O-Diacetylbritannilactone; Compound 2) exhibits potential NO inhibition effect. Britannilactone diacetate exhibits activity against NO production induced by LPS in BV-2 microglial cells with the EC50 value of 6.3 μM. Britannilactone diacetate exhibits a favorable blood-brain barriers (BBB) penetration and absorption, distribution, metabolism, excretion, and toxicity (ADMET) property[1].
Shipping	Room temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	350.41
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Neurological Disease
Solubility	10 mM in DMSO
Target	NO Synthase
Manufacturers Target	NO Synthase
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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