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Methylophiopogonanone B

Methylophiopogonanone B

Item no.	HY-N2438-5mg
Manufacturer	MedChem Express
CASRN	74805-91-7
Amount	5 mg
Quantity options	10 mM x 1 mL 10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.84
Formula	C19H20O5
Citations	[1]Wang Y, et al. Homoisoflavonoids and the Antioxidant Activity of Ophiopogon japonicus Root.<br/>[2]Ito Y, et al. A novel agent, methylophiopogonanone B, promotes Rho activation and tubulin depolymerization. Mol Cell Biochem. 2007 Mar;297(1-2):121-9. Epub 2006 Oct 7.
Smiles	O=C1[C@H](CC2=CC=C(OC)C=C2)COC3=C(C)C(O)=C(C)C(O)=C13
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	74805-91-7
Available
Product Description	Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas, shows high antioxidant ability[1]. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation[2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
MolecularWeight	328.36
Clinical Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Ras
Manufacturers Target	Ras
Manufacturers Pathway	GPCR/G Protein; MAPK/ERK Pathway
Manufacturers Product type	Natural Products

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HY-N2438-5mg-safety-datasheet.pdf