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Pterosin B

Pterosin B

Item no.	HY-N1570-10mg
Manufacturer	MedChem Express
CASRN	34175-96-7
Amount	10 mg
Quantity options	10mM*1 ml 10 mg 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.92
Formula	C14H18O2
Citations	[1]Hannah R.Dexter, et al. A concise stereoselective synthesis of pterosin B. Tetrahedron Letters, Volume 59, Issue 49, 5 December 2018, Pages 4323-4325.<br/>[2]Yahara Y, et al. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Nat Commun. 2016 Mar 24;7:10959.
Smiles	O=C1[C@H](C)CC2=C1C(C)=C(CCO)C(C)=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	34175-96-7
Available
Product Description	Pterosin B, a indanone found in bracken fern (Pteridium aquilinum), is an inhibitor of salt-inducible kinase 3 (Sik3) signaling. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	218.29
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : 250 mg/mL (ultrasonic)
Target	Salt-inducible Kinase (SIK)
Manufacturers Target	Salt-inducible Kinase (SIK)
Isoform	SIK3
Manufacturers Pathway	Immunology/Inflammation
Manufacturers Product type	Natural Products

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HY-N1570-10mg-safety-datasheet.pdf