Comparison

erythro-Austrobailignan-6 European Partner

Item no. HY-N11536-1ea
Manufacturer MedChem Express
CASRN 114127-24-1
Amount 1 ea
Category
Type Inhibitor
Specific against other
Formula C20H24O4
Citations [1]Han JH, et al. Erythro-austrobailignan-6 down-regulates HER2/EGFR/integrinβ3 expression via p38 activation in breast cancer. Phytomedicine. 2017 Jan 15;24:24-30. <br>[2]Lee YK, et al. Inhibition of DNA topoisomerases I and II and cytotoxicity by lignans from Saururus chinensis. Arch Pharm Res. 2009 Oct;32(10):1409-15.
Smiles COC(C=C1C[C@@H](C)[C@@H](C)CC2=CC=C(OCO3)C3=C2)=C(C=C1)O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
erythro-Austrobailignan-6 is an orally active anti-cancer agent. erythro-Austrobailignan-6 inhibits DNA topoisomerase I and II activity. erythro-Austrobailignan-6 induces cell apoptosis and increases phosphorylation of p38 and JNK[1][2].
Shipping
Room temperature
MolecularWeight
328.40
Clinical_Information
No Development Reported
Manufacturers Research_Area
Cancer
Solubility
10 mM in DMSO
Manufacturers Target
Apoptosis; Topoisomerase
Pathway
Apoptosis; Cell Cycle/DNA Damage
Manufacturers Product type
Natural Products

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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