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L-Leucine

L-Leucine

Item no.	HY-N0486-500mg
Manufacturer	MedChem Express
CASRN	61-90-5
Amount	500 mg
Quantity options	100 mg 10 mMx1 mL 250 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.79
Formula	C6H13NO2
Citations	[1]Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. [2]Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. [3]Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17.
Smiles	N[C@@H](CC(C)C)C(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Leucine
Available
Product Description	L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	131.17
Clinical Information	Launched
Manufacturers Research Area	Metabolic Disease
Solubility	H2O : 8.33 mg/mL (ultrasonic)
Target	Endogenous Metabolite; mTOR
Manufacturers Target	Endogenous Metabolite; mTOR
Isoform	Human Endogenous Metabolite; Microbial Metabolite; mTORC1
Manufacturers Pathway	Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Manufacturers Product type	Natural Products

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HY-N0486-500mg-safety-datasheet.pdf