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Thiocolchicoside

Thiocolchicoside

Item no.	HY-N0301-10mM
Manufacturer	MedChem Express
CASRN	602-41-5
Amount	10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.54
Formula	C27H33NO10S
Citations	[1]Carta M, et al. The muscle relaxant thiocolchicoside is an antagonist of GAB<sub>A</sub>A receptor function in the central nervous system. Neuropharmacology. 2006 Sep;51(4):805-15.
Smiles	CSC1=CC=C2C3=C(OC)C(OC)=C(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C=C3CC[C@H](NC(C)=O)C2=CC1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	563.62
Clinical_Information	Phase 4
Manufacturers Research_Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 250 mg/mL (ultrasonic)\|H2O : 50 mg/mL (ultrasonic)
Manufacturers Target	GABA Receptor
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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